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HealthSheets™

DENOSUMAB/XGEVA INJECTIONS

 

Why am I getting this injection?

You and your physician have decided that preventing SRE's (skeletal related events) - bone fractures or spinal compression - is an important part of treating your prostate cancer.

  

 Prior to the first injection

You will need to be evaluated by your dentist for any necessary dental work. We will need a letter from your dentist stating that you can start your treatment. We do this to help protect you from the low risk of developing OJN (osteonecrosis of the jaw) which can occur if dental work is done while receiving this medication.

 During Treatment

You will  recieve this injection every 4 weeks for about a year. During that time and beyond there are several things that we recommend:

  • during treatment you may feel fatiqued - this is normal - if debilitating please call your urologist

  • proper oral hygiene and routine dental care

  • taking supplements of calcium, magnesium and Vit D. We will check you calcium and vitamin D levels by drawing blood work periodically. You may be required to take higher doses than the initially recommended doses of Calcium 1200mg every day and 800Units of Vitamin D every day.

  • participating in our ADT (Androgen Deprivation Therapy) program which will provide you access to oversite of the effects of your cancer treatment medications, nutritional counseling and physical therapy for bone strengthening.

 Please report these symptoms to your Urologist while receiving Xgeva:

  • symptoms of hypocalcemia (low calcium) - paresthesias or muscle stiffness, twitching, spasms or cramps             

  • symptoms of OJN (osteonecrosis of the jaw) - pain, numbness, swelling or drainage from the jaw, mouth or teeth

  • persistant pain or slow healing of the mouth or jaw after dental surgery

  • shortness of breath

 

If you have questions or concerns, please call 303-825-8822