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Medications

Apalutamide Oral Tablet 60 mg

Uses

For treating cancer.

Instructions

Swallow the medicine without crushing or chewing it.

If needed, the medicine may be mixed in 4 ounces (120 mL) of applesauce. Stir the mixture but make sure not to crush the tablets. Wait 15 minutes, and then stir the mixture again. Wait another 15 minutes and stir the mixture for a third time. Make sure the tablets are well mixed with no solid chunks remaining. Swallow the mixture right away using a spoon. After taking the mixture, rinse the container with 2 ounces (60 mL) of water and drink the mixture right away. Repeat the rinse to make sure that the full dose of the medication is taken.

Keep the medicine in its original container.

This medicine may be taken with or without food.

It is very important that you take the medicine at about the same time every day. It will work best if you do this.

Store at room temperature in a dry place. Do not keep in the bathroom.

Keep the medicine away from heat and light.

Keep the desiccant (drying) packet in the bottle and keep the bottle closed tightly.

Please ask your doctor, nurse, or pharmacist how to discard unused medicines safely.

It is important that you keep taking each dose of this medicine on time even if you are feeling well.

If you forget to take a dose on time, take it as soon as you remember. If you don't remember until the next day, do not take the missed dose. Return to your normal dosing schedule. Do not take 2 doses of this medicine at one time.

Please tell your doctor and pharmacist about all the medicines you take. Include both prescription and over-the-counter medicines. Also tell them about any vitamins, herbal medicines, or anything else you take for your health.

If your symptoms do not improve or they worsen while on this medicine, contact your doctor.

Talk to your doctor before taking other medicines, including aspirins and ibuprofen containing products. Speak to your doctor about which medicines are safe to use while you are on this medicine.

Do not suddenly stop taking this medicine. Check with your doctor before stopping.

Use effective birth control to avoid pregnancy.

It is very important that you follow your doctor's instructions for all blood tests.

It is very important that you keep all appointments for medical exams and tests while on this medicine.

Cautions

This medicine is not approved for use by women.

Tell your doctor and pharmacist if you ever had an allergic reaction to a medicine. Symptoms of an allergic reaction can include trouble breathing, skin rash, itching, swelling, or severe dizziness.

This medicine is associated with a rare but very serious medical condition. Please speak with your doctor about symptoms you should look out for while on this medicine. Notify your doctor immediately if you develop those symptoms.

Some patients taking this medicine have experienced serious side effects. Please speak with your doctor to understand the risks and benefits associated with this medicine.

This medicine has been associated with a rare but serious skin rash. If you notice any red, peeling or blistered skin, contact your doctor immediately.

This medicine is associated with an increased risk for seizures. Please ask your doctor whether you may be at risk for having a seizure while on this medicine.

Do not use the medication any more than instructed.

If you miss your period while on this medicine, contact your doctor.

This medicine may reduce your body's ability to fight infections. Try to avoid contact with people with colds, flu or other infections.

This medicine may damage sperm. Men should use reliable birth control while taking this medicine.

Men with a pregnant partner must wear a condom during sexual activity while taking this medicine and for 3 months after stopping to prevent harm to the developing baby.

Men should continue using birth control for at least 3 months after finishing this medicine.

Women who are pregnant or in their childbearing years should not touch or handle this medicine. This medicine can be absorbed through the woman's skin and harm the unborn baby.

Do not donate sperm during treatment and for 3 months after last dose.

Ask your pharmacist if this medicine can interact with any of your other medicines. Be sure to tell them about all the medicines you take.

Please tell all your doctors and dentists that you are on this medicine before they provide care.

Do not start or stop any other medicines without first speaking to your doctor or pharmacist.

Do not share this medicine with anyone who has not been prescribed this medicine.

Always refill this medicine before it runs out.

Side Effects

The following is a list of some common side effects from this medicine. Please speak with your doctor about what you should do if you experience these or other side effects.

  • decreased appetite
  • diarrhea
  • swelling of the legs, feet, and hands
  • lack of energy and tiredness
  • feeling of heat or flushing
  • high blood pressure
  • pain in the joints
  • nausea
  • weight loss

Call your doctor or get medical help right away if you notice any of these more serious side effects:

  • increased risk for bone fractures
  • chest pain
  • skin irritation such as redness, itching, rash, or burning
  • seizures
  • shortness of breath
  • symptoms of stroke (such as one-sided weakness, slurred speech, confusion)

A few people may have an allergic reactions to this medicine. Symptoms can include difficulty breathing, skin rash, itching, swelling, or severe dizziness. If you notice any of these symptoms, seek medical help quickly.

Extra

Please speak with your doctor, nurse, or pharmacist if you have any questions about this medicine.

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IMPORTANT NOTE: This document tells you briefly how to take your medicine, but it does not tell you all there is to know about it.Your doctor or pharmacist may give you other documents about your medicine. Please talk to them if you have any questions.Always follow their advice. There is a more complete description of this medicine available in English.Scan this code on your smartphone or tablet or use the web address below. You can also ask your pharmacist for a printout. If you have any questions, please ask your pharmacist.


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