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Medications

Amitriptyline Hydrochloride/Perphenazine Oral Tablet 25 mg/4 mg

Uses

For depression.

Instructions

To relieve dry mouth while taking this medicine, try chewing gum or sucking on hard candy or ice chips. Drink extra water or use a saliva substitute.

It is very important that you take the medicine at about the same time every day. It will work best if you do this.

Store at room temperature in a dry place. Do not keep in the bathroom.

Keep the medicine away from heat and light.

Tell your doctor if you have severe or persistent sweating, diarrhea or vomiting. These can increase your risk of a serious side effect.

This medicine may cause you to become more sensitive to the sun. Use sunscreen or wear protective clothing when you are exposed to the sun.

It may take several weeks for this medicine to fully work.

It is important that you keep taking each dose of this medicine on time even if you are feeling well.

If you forget to take a dose on time, take it as soon as you remember. If it is almost time for the next dose, do not take the missed dose. Return to your normal dosing schedule. Do not take 2 doses of this medicine at one time.

Please tell your doctor and pharmacist about all the medicines you take. Include both prescription and over-the-counter medicines. Also tell them about any vitamins, herbal medicines, or anything else you take for your health.

If your symptoms do not improve or they worsen while on this medicine, contact your doctor.

Do not suddenly stop taking this medicine. Check with your doctor before stopping.

If you need to stop this medicine, your doctor may wish to gradually reduce the dosage before stopping.

This medicine may affect your blood sugar levels. If you have diabetes, talk to your doctor before changing the dose of your diabetes medicine.

It is very important that you follow your doctor's instructions for all blood tests.

It is very important that you keep all appointments for medical exams and tests while on this medicine.

Cautions

Tell your doctor and pharmacist if you ever had an allergic reaction to a medicine. Symptoms of an allergic reaction can include trouble breathing, skin rash, itching, swelling, or severe dizziness.

This medicine is associated with a rare but very serious medical condition. Please speak with your doctor about symptoms you should look out for while on this medicine. Notify your doctor immediately if you develop those symptoms.

Some patients taking this medicine have experienced serious side effects. Please speak with your doctor to understand the risks and benefits associated with this medicine.

Do not use the medication any more than instructed.

This medicine may cause dizziness or fainting, especially after exercising or in hot weather. Be very careful when standing or sitting up quickly.

If possible, avoid using with marijuana or other medicines that can cause dizziness or drowsiness. These include allergy/cold products, muscle relaxers, sleep aids, and pain relievers.

Your ability to stay alert or to react quickly may be impaired by this medicine. Do not drive or operate machinery until you know how this medicine will affect you.

Speak with your doctor before taking any medicine with aspirin.

Do not drink beverages with alcohol while on this medicine.

Avoid becoming overheated during exercise or other activities. Try to stay cool in hot weather.

Family should check on the patient often. Call the doctor if patient becomes more depressed, has thoughts of suicide, or shows changes in behavior.

Call the doctor if there are any signs of confusion or unusual changes in behavior.

Tell the doctor or pharmacist if you are pregnant, planning to be pregnant, or breastfeeding.

Ask your pharmacist if this medicine can interact with any of your other medicines. Be sure to tell them about all the medicines you take.

Please tell all your doctors and dentists that you are on this medicine before they provide care.

Do not start or stop any other medicines without first speaking to your doctor or pharmacist.

Call your doctor right away if you notice slow or shallow breathing.

Do not share this medicine with anyone who has not been prescribed this medicine.

This medicine can cause serious side effects in some patients. Important information from the U.S. Food and Drug Administration (FDA) is available from your pharmacist. Please review it carefully with your pharmacist to understand the risks associated with this medicine.

Side Effects

The following is a list of some common side effects from this medicine. Please speak with your doctor about what you should do if you experience these or other side effects.

  • blurry vision
  • constipation
  • dizziness
  • drowsiness or sedation
  • dry mouth
  • lightheadedness
  • difficulty or discomfort urinating
  • weight gain

Call your doctor or get medical help right away if you notice any of these more serious side effects:

  • severe or persistent abdominal pain
  • agitated feeling or trouble sleeping
  • loss of balance
  • change in behavior
  • increased risk of bruising and bleeding
  • breast pain or swelling
  • chest pain
  • confusion
  • coughing up blood or vomit that looks like coffee grounds
  • pain in the eye
  • face appearing mask-like
  • fainting
  • high fever
  • fast or irregular heart beats
  • unusual strong urges - such as increased need to shop, gamble, or have sex
  • irritability
  • signs of kidney damage (such as bloody or bubbly urine, or changes in urine color or amount)
  • memory problems or loss
  • menstruation changes (missed or fewer periods)
  • mood changes
  • uncontrollable movement of face, tongue, arms or legs
  • muscle aches, spasms or abnormal movements
  • muscle pain
  • tight or rigid muscles
  • muscle weakness
  • restlessness
  • seizures
  • problems with sexual functions or desire
  • shakiness
  • blistering or peeling of the skin
  • talking quickly
  • dark, tarry stool
  • symptoms of stroke (such as one-sided weakness, slurred speech, confusion)
  • suicidal thoughts
  • difficulty swallowing
  • sweating
  • dark urine
  • blurring or changes of vision
  • severe or persistent vomiting

A few people may have an allergic reactions to this medicine. Symptoms can include difficulty breathing, skin rash, itching, swelling, or severe dizziness. If you notice any of these symptoms, seek medical help quickly.

Extra

Please speak with your doctor, nurse, or pharmacist if you have any questions about this medicine.

https://krames.meducation.com/V2.0/fdbpem/9047https://krames.meducation.com/V2.0/fdbpem/9047

IMPORTANT NOTE: This document tells you briefly how to take your medicine, but it does not tell you all there is to know about it.Your doctor or pharmacist may give you other documents about your medicine. Please talk to them if you have any questions.Always follow their advice. There is a more complete description of this medicine available in English.Scan this code on your smartphone or tablet or use the web address below. You can also ask your pharmacist for a printout. If you have any questions, please ask your pharmacist.


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